Biologic therapy-induced pemphigus*
نویسندگان
چکیده
An Bras Dermatol. 2017;92(4):584-95. Dear editor, Pemphigus is an autoimmune bullous disease that can affect the skin and mucous membranes, mediated by autoantibodies against desmosomal desmogleins, the main adhesion structures Marina Zoega Hayashida1 Jhonatan Rafael Siqueira Pinheiro1 Milvia Maria Simões e Silva Enokihara2 Mônica Ribeiro de Azevedo Vasconcellos1 t Biologic therapy-induced pemphigus*
منابع مشابه
Trigeminal trophic syndrome*
An Bras Dermatol. 2017;92(4):584-95. How to cite this article: Hayashida MZ, Pinheiro JRS, Enokihara MMSS, Vasconcellos MRA. Biologic therapy-induced pemphigus. An Bras Dermatol. 2017;92(4):591-3. Mailing address: Mônica Ribeiro de Azevedo Vasconcellos Av. Borges Lagoa, 508 -Vila Clementino 04038-000 -São Paulo, SP Brazil E-mail: [email protected] in adults.6 The metabolism of both drugs i...
متن کاملDapsone in the treatment of pemphigus vulgaris: adverse effects and its importance as a corticosteroid sparing agent*
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids include, among others, dapsone. This drug is not without side effects and its use requires clinical and l...
متن کاملفراوانی و عوامل خطرساز دیابت بهدنبال شروع درمان با گلوکوکورتیکوئید در مبتلایان به پمفیگوسولگاریس در بیمارستان رازی تهران
Background and Aim: Pemphigus vulgaris is the most common autoimmune blistering disease. Prednisone, commonly in combination with an immunosuppressive adjuvant such as azathioprine or cyclophosphamide, is the standard treatment for pemphigus vulgaris. Approximately 5% to 15% of mortality of the disease is due to the complications of corticosteroids therapy. The aim of this study was to determin...
متن کاملMinocycline-induced hyperpigmentation in patients with pemphigus and pemphigoid.
BACKGROUND Immunosuppressive medications typically used to treat the immunobullous disorders pemphigus vulgaris, pemphigus foliaceous, and bullous pemphigoid can have serious adverse effects. The tetracycline family of antibiotic drugs has been shown to be effective in the treatment of these conditions with a more favorable side effect profile. Minocycline hydrochloride use has been associated ...
متن کاملDapsone as a second glucocorticoid-sparing agent in addition to azathioprine in treatment of pemphigus vulgaris
Background and aim: Pemphigus vulgaris is an autoimmune vesiculobullous disorder. Prior to the advent of glucocorticoid therapy, it was often fatal. Now its mortality and morbidity is due to highdose glucocorticoid complications rather than the disease itself. This study was aimed to determine the effect of dapsone as a second adjuvant in the treatment of pemphigus vulgaris.Materials and method...
متن کامل